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Single-cell transcriptome atlas and genome-wide Mendelian randomization reveal chemokine involvement in diverse immune cells in type 2 diabetes
Studies & Findings

Single-cell transcriptome atlas and genome-wide Mendelian randomization reveal chemokine involvement in diverse immune cells in type 2 diabetes

Skyler JS, Bakris GL, Bonifacio E, Darsow T, Eckel RH, Groop L, et al. Differentiation of diabetes by pathophysiology, natural history, and prognosis. Diabetes. 2017;66:241–55. CAS  PubMed  Google Scholar  Wondmkun YT. Obesity, insulin resistance, and type 2 diabetes: associations and therapeutic implications. Diabetes, Metab Syndr Obes. 2020;13:3611–6. Bartlett DB, Slentz CA, Willis LH, Hoselton A,

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Identification of clinical diagnostic and immune cell infiltration characteristics of acute myocardial infarction with machine learning approach
Studies & Findings

Identification of clinical diagnostic and immune cell infiltration characteristics of acute myocardial infarction with machine learning approach

Identification of dysregulated expressed genes As the work flow shown in Fig. S1, three GEO data sets (GSE61145, GSE34198, and GSE66360) were included in this study. A total of 697, 163, and 734 up-regulated and 679, 72, and 741 downregulated genes were obtained in GSE34198, GSE61145, and GSE66360 respectively (Fig. 1A). According to the heatmap shown

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