chemokine

Studies & Findings

Differential expression pattern of CC chemokine receptor 7 guides precision treatment of hepatocellular carcinoma

CCR7 is highly expressed in tumor cells and predicts poor prognosis of HCC patients Our previous study has proved that CC-chemokine receptor like 1 (CCRL1) impairs chemotactic events associated with CCR7 in the progression and metastasis of HCC.24 In order to explore the function of another CC-chemokine CCL21/CCR7 axis in HCC, we investigated the complex

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Studies & Findings

Single-cell transcriptome atlas and genome-wide Mendelian randomization reveal chemokine involvement in diverse immune cells in type 2 diabetes

Skyler JS, Bakris GL, Bonifacio E, Darsow T, Eckel RH, Groop L, et al. Differentiation of diabetes by pathophysiology, natural history, and prognosis. Diabetes. 2017;66:241–55. CAS  PubMed  Google Scholar  Wondmkun YT. Obesity, insulin resistance, and type 2 diabetes: associations and therapeutic implications. Diabetes, Metab Syndr Obes. 2020;13:3611–6. Bartlett DB, Slentz CA, Willis LH, Hoselton A,

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